Patent · US Expired

Method for the inhibition of function of STAT transcription factors

US7002003B1 · kind B1 · utility

1Cited by
19References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 30, 1999
Grant dateFeb 21, 2006
Priority date
Expiry dateJul 30, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.