Process for the preparation of citalopram
US7002025B2 · kind B2 · utility
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4References
35Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 7, 2001 |
| Grant date | Feb 21, 2006 |
| Priority date | — |
| Expiry date | Dec 14, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Preparation of citalopram comprises the steps of: (a) converting the compound of Formula (I) to a compound of Formula (II), wherein R in Formula (I) represents a C2 to C5 alkylene group which may be substituted or unsubstituted, and R1 in the compounds of Formula (II) represents a carboxylic acid group or a salt or an ester thereof; and (b) converting the compound of Formula (II) to form citalopram or a pharmaceutically acceptable salt thereof, or a direct conversion of the compound of Formula (I) to citalopram
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.