Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides

US7005420B2 · kind B2 · utility

Assignee

• IPSEN MANUFACTURING IRELAND LIMITED · IE

Inventors

• Shalaby W. Shalaby · Anderson, US
• Ruth M. Russell · Dublin, IE
• Jacques-Pierre Moreau · Upton, US
• Steven A. Jackson · Newton, US
• Francis Ignatious · Milford, US

Key dates

• Filing date: Jul 27, 2004
• Grant date: Feb 28, 2006
• Expiry date: Jul 28, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08L5/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.