Method and apparatus for desolvating ions for introduction into a FAIMS analyzer region
US7005633B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 7, 2003 |
| Grant date | Feb 28, 2006 |
| Priority date | — |
| Expiry date | Feb 8, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/3504
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are an apparatus and a method for separating ions produced at an electrospray ionization source, based upon the high field mobility properties of the ions. An apparatus according to the instant invention includes a high field asymmetric waveform ion mobility spectrometer (FAIMS) having an analyzer region defined by a space between an inner electrode (32) and an outer electrode (34). In particular, the outer electrode includes an ion inlet (38) for introducing ions into a first portion of analyzer region and an ion outlet (56) for extracting ions from a second portion of the analyzer region. The FAIMS is characterized in that a gas-directing conduit (48) is provided through at least a portion of the inner electrode. In particular, the gas-directing conduit includes an opening at a first end thereof for supporting fluid communication between the gas-directing conduit and the first portion of the analyzer region. The gas-directing conduit is adapted at a second end thereof opposite the first end for supporting fluid communication between a gas source and the gas-directing conduit. The opening is orientated relative to the ion inlet such that gas provided through the gas-dire…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.