Patent · US Expired

End modified thermal responsive hydrogels

US7008628B2 · kind B2 · utility

24Cited by
8References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 13, 2001
Grant dateMar 7, 2006
Priority date—
Expiry dateOct 22, 2022

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K47/34
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A pharmaceutic composition includes a pharmaceutically acceptable carrier, comprising a reverse thermally viscosifying polymer. The polymer includes a linear block copolymer, wherein at least one block comprises a poloxamer; and at least one block comprises a biocompatible polymer or oligomer, in an aqueous medium. The composition also includes an active agent which imparts a pharmaceutic or cosmetic effect. The composition viscosifies in response to an environmental stimulus. The composition is suitable for administration of the pharmaceutical agent across dermal, otic, rectal, vaginal, ophthalmic, esophageal and nasal mucosal membranes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.