Composition and method for reducing adverse interactions between phenothiazine derivatives and plasma using cyclodextrins
US7008934B2 · kind B2 · utility
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Key dates
| Filing date | Jun 26, 2002 |
| Grant date | Mar 7, 2006 |
| Priority date | — |
| Expiry date | Jun 26, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are provided for reducing adverse reactions as a result of parenteral administration of certain phenothiazine derivatives such as promethazine hydrochloride. The active compound may be admixed with an effective amount of one or more cyclodextrin derivatives, and if desired, one or more non-ionic surfactants such as the partial esters of sorbitol and the polyoxyethylene oxides of long chain fatty acids such as the polysorbates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.