Patent · US Expired

1-(Pyrrolidin-1-ylmethyl)-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives

US7008943B2 · kind B2 · utility

1Cited by
25References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 5, 2003
Grant dateMar 7, 2006
Priority date
Expiry dateMay 5, 2023

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/65583
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to 1-pyrrolidin-1-ylmethyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives that modulate the activity of protein kinases (“PKs”). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.