Dosage forms having a barrier layer to laser ablation
US7011850B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 13, 2000 |
| Grant date | Mar 14, 2006 |
| Priority date | — |
| Expiry date | Jan 18, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A dosage form for delivery of a therapeutic agent to a subject is described. The dosage form contains: (a) an outer wall defining an interior compartment; (b) within the interior compartment, a therapeutic agent; (c) at least one exit orifice formed by laser ablation of the outer wall for release of the agent therethrough, and (d) a barrier layer disposed between the outer wall and the interior compartment in at least a region corresponding to the exit orifice. The barrier layer comprises a material that allows the barrier layer to remain intact during laser-formation of the at least one exit orifice in the outer wall. Also disclosed is a method for controlling the depth of laser ablation of a dosage form during laser formation of an exit orifice in an outer wall of the dosage form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.