Random array of micro-spheres for the analysis of nucleic acids
US7011945B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 21, 2001 |
| Grant date | Mar 14, 2006 |
| Priority date | — |
| Expiry date | Jun 4, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG16B25/00
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A method of identifying nucleic acid samples comprising: providing a mircoarray including a substrate coated with a composition including a population of micro-spheres dispersed in a fluid containing a gelling agent or a precursor to a gelling agent and immobilized at random positions on the substrate, at least one sub-population of said population micro-spheres containing an optical barcode generated from at least one colorant associated with the micro-spheres and including a nucleic acid probe sequence; contacting said array with a target nucleic acid sequence; and detecting the color barcode of said sub-population of micro-spheres due to the interaction of said probe nucleic acid sequence and said target nucleic acid sequence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.