Method of producing solid shape forms containing an active ingredient

US7014810B2 · kind B2 · utility

Assignee

• Abbott GmbH & Co. KG · DE

Inventors

• Harald Krull · Ludwigshafen, DE
• Jörg Rosenberg · Ellerstadt, DE
• Jorg Breitenbach · Mannheim, DE
• Jurgen Hofmann · Spalt, DE
• Rainer Klenz · Herbrechtingen, DE
• Hans Bührle · Schifferstadt, DE

Key dates

• Filing date: Dec 15, 2000
• Grant date: Mar 21, 2006
• Expiry date: Dec 27, 2020

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B29K2105/0035
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to an apparatus for producing solid active ingredient-containing forms from an active ingredient-containing formulation which comprises at least one polymeric binder. The apparatus according to the invention has at least one extruder 1 for continuous plastication of the formulation and at least two injection units 2 which are provided separate from one another, each of which is connected to the extruder 1, and through which the formulation can be injected into at least one mold 3. In the process according to the invention for producing solid active ingredient-containing forms from an active ingredient-containing formulation which comprises at least one binder, the active ingredient-containing formulation is continuously plasticated, the plasticated formulation is fed into an injection unit 21, and the formulation present in this injection unit 21 is injected into a mold 3, and plasticated formulation is fed into another injection molding unit 22, and the formulation present in the other injection molding unit 22 is injected into the mold 3 or another mold.