Patent · US Expired

Amide compounds and medicinal use thereof

US7015218B1 · kind B1 · utility

33Cited by
3References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 10, 2000
Grant dateMar 21, 2006
Priority date
Expiry dateFeb 10, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a compound of the formula wherein R1 is substituted aryl, heteroaryl and the like, R2 and R3 are hydrogen, alkyl, halogen, hydroxyl group and the like, Q is N, CH and the like, W is hydrogen, alkyl, hydroxycarbonylalkyl and the like, X is halogen, cyano, nitro, amino and the like, X′ is hydrogen, halogen, cyano, nitro, and Y is alkyl, hydroxyl group, alkoxy, mercapto and the like and a salt thereof, and a medicine containing the said compound. The compound of the present invention shows a superior inhibitory effect on activated lymphocytes proliferation and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.