Substituted pyrimidinones and pyrimidinthiones
US7015229B2 · kind B2 · utility
2Cited by
1References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 20, 2003 |
| Grant date | Mar 21, 2006 |
| Priority date | — |
| Expiry date | Nov 15, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/726
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to substituted pyrimidinone and pyrimidithione derivatives that bind with high affifnity to CRF1 receptors, including human CRF1 receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety disorders, and depression and stress related disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.