Polynucleotides encoding human persephin and related growth factors
US7015316B1 · kind B1 · utility
1Cited by
9References
4Claims
0Family size
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Key dates
| Filing date | Dec 24, 1998 |
| Grant date | Mar 21, 2006 |
| Priority date | — |
| Expiry date | Dec 24, 2018 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4756
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A novel growth factor, persephin, which belongs to the GDNF/neurturin family of growth factors, is disclosed. The human, mouse and rat amino acid sequences have been identified. Human, mouse and rat persephin genomic DNA sequences have been cloned and sequenced and the respective cDNA sequences identified. In addition, methods for treating degenerative conditions using persephin, methods for detecting persephin gene alterations and methods for detecting and monitoring patient levels of persephin are provided. Methods for identifying additional members of the persephin-neurturin-GDNF family of growth factors are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.