Parallel concentration, desalting and deposition onto MALDI targets
US7015465B2 · kind B2 · utility
5Cited by
14References
22Claims
0Family size
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Key dates
| Filing date | Apr 29, 2004 |
| Grant date | Mar 21, 2006 |
| Priority date | — |
| Expiry date | Apr 29, 2024 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and apparatus for the continuous deposition of RP HPLC eluent, from isocratic or gradient elutions, on to a MALDI target using a parallel sample desalting method, allows increased sensitivity of the MALDI sample by pre-concentration of the analyte, separation of interfering contaminants from the analyte and increased dynamic range of peptide abundance that can be analyzed. The parallel processing of sample material allows greater throughput than that of manual methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.