Patent · US Expired

17α-ALKYL-17β-OXY-ESTRATRIENES AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION, USE OF THE 17α-ALKYL-17β-OXY-ESTRATRIENES FOR THE PRODUCTION OF PHARMACEUTICAL AGENTS AS WELL AS PHARMACEUTICAL PREPARATIONS

US7018994B2 · kind B2 · utility

1Cited by

1References

28Claims

0Family size

Assignee

SCHERING CORPORATION · US

Inventors

Rolf Bohlmann · Berlin, DE
Nikolaus Heinrich · Berlin, DE
Rolf Jautelat · Haan, DE
Jorg Kroll · Berlin, DE
Orlin Petrov · Berlin, DE
Andreas Reichel · Berlin, DE
Jens Hoffmann · Mühlenbeck, DE
Rosemarie Lichtner · Berlin, DE

Key dates

Filing date	Nov 27, 2002
Grant date	Mar 28, 2006
Priority date	—
Expiry date	Nov 27, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J41/0072
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to 17α-alkyl-17β-oxy-estra-1,3,5(10)-trienes that have an antiestrogenic action with general formula I. In addition, the invention also relates to 17-oxo-estra-1,3,5(10)-trienes as well as 17β-hydroxy-estra-1,3,5(10)-trienes as intermediate products in the production of the estratrienes according to the invention. The invention also relates to the use of 17α-alkyl-17β-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations that contain at least one 17α-alkyl-17β-oxy-estratriene as well as at least one pharmaceutically compatible vehicle.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.