Modulators of Protein Tyrosine Phosphatases (PTPases)
US7019026B1 · kind B1 · utility
19Cited by
2References
74Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 2000 |
| Grant date | Mar 28, 2006 |
| Priority date | — |
| Expiry date | Sep 11, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are novel compounds, novel compositions, methods of their use, and methods of their manufacture, where such compounds of Formula 1 are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPases) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like, wherein n, m, X, Y, R1, R2, R3, R4, R5 and R6 are defined more fully in the description. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, and other diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.