Ring-interferometric sol-gel bio-sensor

US7019847B1 · kind B1 · utility

Assignee

• The United States of America as represented by the Administrator of the National Aeronautics and Space Administration · US

Inventors

• Gregory Bearman · Pasadena, US
• David Cohen · Stamford, US

Key dates

• Filing date: Dec 9, 2003
• Grant date: Mar 28, 2006
• Expiry date: Nov 18, 2024

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/45
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A biosensor embodying the invention includes a sensing volume having an array of pores sized for immobilizing a first biological entity tending to bind to a second biological entity in such a manner as to change an index of refraction of the sensing volume. The biosensor further includes a ring interferometer, one volumetric section of the ring interferometer being the sensing volume, a laser for supplying light to the ring interferometer, and a photodetector for receiving light from the interferometer.