Methods for cell-based combinatorial logic
US7020560B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 6, 2001 |
| Grant date | Mar 28, 2006 |
| Priority date | — |
| Expiry date | Sep 6, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06N3/002
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for cell-based combinatorial logic includes the steps of providing at least one genetically engineered cell, the genetically engineered cell having at least one transcriptional unit. The transcriptional unit includes a gene and a promoter, wherein application of a stimulus to the promoter results in the expression of a gene product. An energetic or chemical stimulus is applied to activate the promoter, wherein the detection of an output signal corresponds to the presence of a gene product. The cell can include a plurality of transcriptional units configured to form logic gates. The logic gates of a plurality of cells can be operably interconnected by release of output signals, such as chemical stimuli.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.