Administration of a thiol-based chemoprotectant compound
US7022315B2 · kind B2 · utility
14Cited by
10References
2Claims
0Family size
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Key dates
| Filing date | Apr 26, 2001 |
| Grant date | Apr 4, 2006 |
| Priority date | — |
| Expiry date | Dec 14, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of administration of a thiol-based chemoprotectant agent including NAC (N-acetylcysteine) and STS (sodium thiosulfate) that markedly affects biodistribution and protects against injury from diagnostic or therapeutic intra-arterial procedures. A method for treating or mitigating the side effects of cytotoxic cancer therapy for tumors located in the head or neck and brain tumors. The thiol-based chemoprotectant agent is administered intra-arterially with rapid and first pass uptake in organs and tissues other than the liver.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.