Treatment of rumen acidosis with α-amylase inhibitors
US7022684B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2002 |
| Grant date | Apr 4, 2006 |
| Priority date | — |
| Expiry date | Aug 2, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/702
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of rumen acidosis; a method of treatment of rumen acidosis which comprises administration of an effective amount of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase to a ruminant; a formulation suitable for the treatment of rumen acidosis in an animal which comprises an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in admixture with a suitable excipient, diluent or carrier selected with regard to the intended route of administration and standard pharmaceutical/veterinary/farming practice; screening methods useful in the identification of a suitable inhibitor of a bacterial α-amylase and/or α-glucosidase for the treatment of acidosis in a ruminant; a process for improving ruminant milk quality and/or quantity which comprises treatment of a ruminant with an effective amount of an inhibitor of bacterial α-amylase and/or α-glucosidase; a compound of the formula I: or veterinarily acceptable salt, solvate (including hydrate) or prodrug thereof; and processes to make an effe…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.