Patent · US Expired

Polyketides and antibiotics

US7022825B2 · kind B2 · utility

6Cited by
2References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 8, 2002
Grant dateApr 4, 2006
Priority date
Expiry dateFeb 25, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C327/30
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.