In-vivo diagnostic method by means of near infrared radiation

US7025949B2 · kind B2 · utility

Assignee

• Institut fur Diagnostikforschung GmbH an der Freien Universitat Berlin · DE

Inventors

• Kai Licha · Berlin, DE
• Bjorn Riefke · Berlin, DE
• Wolfhard Semmler · Glienicke, DE
• Ulrich Speck · Berlin, DE
• Christoph-Stephan Hilger · Berlin, DE

Key dates

• Filing date: May 7, 2001
• Grant date: Apr 11, 2006
• Expiry date: May 7, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09B69/105
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to an in-vivo diagnostic method based on near infrared radiation (NIR radiation) that uses water-soluble dyes and their biomolecule adducts, each having specific photophysical and pharmaco-chemical properties, as a contrast medium for fluorescence and transillumination diagnostics in the NIR range, to new dyes and pharmaceuticals containing such dyes.