Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
US7030082B2 · kind B2 · utility
23Cited by
89References
72Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 5, 2003 |
| Grant date | Apr 18, 2006 |
| Priority date | — |
| Expiry date | Aug 3, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions that include a drug and/or drug-oligomer conjugate, a fatty acid component and a bile salt component, or a bile salt component without a fatty acid component are described. The drug can be covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component, when together, can be present in a weight-to-weight ratio of between 1:15 and 15:1 or any value between. Methods of treating diseases in a subject in need of such treatment using the pharmaceutical compositions of this invention are also provided, as well as methods of providing such pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.