Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and QS-21
US7030094B2 · kind B2 · utility
1Cited by
11References
27Claims
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Key dates
| Filing date | Jun 21, 2002 |
| Grant date | Apr 18, 2006 |
| Priority date | — |
| Expiry date | Sep 19, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides pharmaceutical compositions, particularly vaccine compositions, employing an adjuvant system comprising RC-529 (an aminoalkyl glucosaminide phosphate compound) and QS-21 (a saponin). Such compositions synergistically enhance the immune response in a mammal to a co-administered antigen. Also provided are methods of using the compositions in the treatment of various human diseases, including cancer, microbial infections and autoimmune disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.