Topical oestroprogestational compositions with a systemic effect
US7030104B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 14, 2001 |
| Grant date | Apr 18, 2006 |
| Priority date | — |
| Expiry date | Dec 2, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P15/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the field of therapeutic chemistry and more especially to the realization of new galenic forms intended to be applied on the skin.More particularly it relates to a topical hormonal composition with a systemic effect for the hormonal treatment of the perimenopause and of the menopause as well as for the treatment of the ovarian hormonal deficiencies in women with amenorrhea, characterized in that it comprises, as active ingredients, a progestogen derived from 19-nor progesterone and estradiol or one of its derivatives, a vehicle which allows the systemic passage of said active ingredients, chosen from the group constituted by a solubilizing agent, an absorption promoting agent, a film-forming agent, a gelling agent and their mixtures, in combination or in a mixture with suitable excipients for the realization of a gelled and/or film-forming pharmaceutical form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.