Process for making camptothecin derivatives
US7030243B1 · kind B1 · utility
1Cited by
2References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 28, 2004 |
| Grant date | Apr 18, 2006 |
| Priority date | — |
| Expiry date | Oct 28, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for synthesizing highly lipophilic derivatives of camptothecin. The process includes reacting dissolved, underivatized camptothecin with a silylated heterocyclic compound in a modified Minisci-type alkylation reaction to produce 7-substituted derivatives of camptothecin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.