Caenorhabditis elegans strain HD8: a mutant exhibiting constitutive pharyngeal pumping
US7030290B2 · kind B2 · utility
14Cited by
1References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 11, 2003 |
| Grant date | Apr 18, 2006 |
| Priority date | — |
| Expiry date | Apr 6, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/43534
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods of screening compounds for potential pharmacological activity using nematode worms, principally but not exclusively the nematode C. elegans. Specifically, the invention relates to the use of nematodes modified to have certain characteristics which provide advantages for compound screening, such as constitutive pharyngeal pumping, increased gut permeability or altered gut molecular transport. Methods for selecting suitably modified nematodes from a population of nematodes are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.