Therapeutic polypeptides, nucleic acids encoding same, and methods of use

US7034132B2 · kind B2 · utility

Inventors

• David Anderson · Gladsmuir, GB
• Jason Baumgartner · New Haven, US
• Ferenc Boldog · North Haven, US
• Stacie Casman · North Haven, US
• Shlomit Edinger · New Haven, US
• Esha Gangolli · Madison, US
• Valerie Gerlach · Branford, US
• Linda Gorman · Branford, US
• Xiaojia Guo · Branford, US
• Tord Hjalt · East Haven, US
• Ramesh Kekuda · Stamford, US
• Li Li · Stanford, US
• John MacDougall · Hamden, US
• Uriel Malyankar · Branford, US
• Isabelle Millet · Milford, US
• Muralidhara Padigaru · Mumbai, IN
• Meera Patturajan · Branford, US
• Carol Pena · New Haven, US
• Luca Rastelli · Guilford, US
• Richard Shimkets · West Haven, US
• David Stone · Guilford, US
• Kimberly Spytek · New Haven, US
• Corine Vernet · North Branford, US
• Edward Voss · Wallingford, US
• Bryan Zerhusen · Branford, US

Key dates

• Filing date: Jun 3, 2002
• Grant date: Apr 25, 2006
• Expiry date: Apr 21, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.