Patent · US Expired

Compounds and methods for the treatment and prevention of bacterial infection

US7037503B2 · kind B2 · utility

16Cited by

9References

10Claims

0Family size

Assignee

President and Fellows of Harvard College · US

Inventors

R. John Collier · Wellesley, US
Bret Sellman · Rochester, US

Key dates

Filing date	May 4, 2001
Grant date	May 2, 2006
Priority date	—
Expiry date	May 4, 2021

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K39/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides mutant forms of pore-forming toxins. These mutant toxins may be used in vaccines for the prevention of bacterial infection. Additionally, dominant negative mutants may be administered as therapeutics for the treatment of bacterial infection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.