Patent · US Expired

Cancer diagnostic method based upon DNA methylation differences

US7037650B2 · kind B2 · utility

52Cited by
3References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 22, 2001
Grant dateMay 2, 2006
Priority date—
Expiry dateNov 18, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6858
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

There is disclosed a cancer diagnostic method based upon DNA methylation differences at specific CpG sites. Specifically, the inventive method provides for a bisulfite treatment of DNA, followed by methylation-sensitive single nucleotide primer extension (Ms-SNuPE), for determination of strand-specific methylation status at cytosine residues.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.