Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis
US7038063B2 · kind B2 · utility
32Cited by
2References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 18, 2003 |
| Grant date | May 2, 2006 |
| Priority date | — |
| Expiry date | Nov 18, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/533
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Atropisomeric energy-transfer dye compounds are disclosed. A variety of molecular biology applications utilize atropisomeric xanthene fluorescent dyes as labels for substrates such as nucleotides, nucleosides, polynucleotides, polypeptides and carbohydrates. Methods include DNA sequencing, DNA fragment analysis, PCR, SNP analysis, oligonucleotide ligation, amplification, minisequencing, and primer extension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.