Elimination of endogenous porcine retrovirus
US7038107B2 · kind B2 · utility
5Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 28, 2002 |
| Grant date | May 2, 2006 |
| Priority date | — |
| Expiry date | Jul 26, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/10022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Porcine nucleic acid sequences flanking potentially infectious porcine endogenous retroviral (PERV) insertion sites have been identified and isolated. The unique flanking sequences include porcine nucleic acid sequences that flank the 3′ end and porcine nucleic acid sequences that flank the 5′ end of PERV insertion sites. The present invention provides compositions and methods for detecting presence of PERV in a sample, particularly those with infectious potential. In addition, the invention relates to breeding of pigs or selection of porcine tissue that is free of infectious PERV for use as a xenotransplant tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.