Fatty acid elongases

US7038112B2 · kind B2 · utility

Assignee

• Miami University · US

Inventors

• Jan Jaworski · Oxford, US
• Martha Post-Beittenmiller · Manchester, US
• James Todd · Walla Walla, US

Key dates

• Filing date: Jun 18, 2001
• Grant date: May 2, 2006
• Expiry date: Jun 18, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/1029
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Nucleic acids are disclosed that encode fatty acid β-keto acyl synthases from plants. Such synthases are effective for producing very long chain fatty acids (VLCFA), e.g., C22 to C26, preferentially saturated but also monounsaturated. Also disclosed are polypeptides encoded by such nucleic acids. Transgenic plants expressing these polypeptides exhibit altered levels of VLCFA in one or more tissues, such as seeds of leaves.