Long oligonucleotide arrays
US7041445B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 15, 1999 |
| Grant date | May 9, 2006 |
| Priority date | — |
| Expiry date | Nov 15, 2019 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2219/00637
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Long oligonucleotide arrays, as well as methods for their preparation and use in hybridization assays, are provided. The subject arrays are characterized in that at least a portion of the probes of the array, and usually all of the probes of the array, are long oligonucleotides, e.g. oligonucleotides having a length of from about 50 to 120 nt. Each long oligonucleotide probe on the array is preferably chosen to exhibit substantially the same high target binding efficiency and substantially the same low non-specific binding under conditions in which the array is employed. The subject arrays find use in a number of different applications, e.g. differential gene expression analysis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.