Orthologues of human receptors and methods of use
US7041463B2 · kind B2 · utility
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Key dates
| Filing date | Sep 9, 2002 |
| Grant date | May 9, 2006 |
| Priority date | — |
| Expiry date | Jan 6, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/705
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for identifying modulators of receptor activity using orthologues of human receptors are described. Additionally, a method for identifying an animal model useful in the screening of potential therapeutic agents is provided. The genes for bradykinin B1 receptors from five mammalian species, vervet monkey, rhesus macaque, tree shrew, dog and pig, as well as the genes for CXCR2 receptors from chimpanzee, gorilla, orangutan, rhesus, vervet and baboon have been cloned and characterized and are described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.