Antibodies binding to polypeptides encoded by developmentally-regulated endothelial cell locus-1
US7041801B1 · kind B1 · utility
1Cited by
9References
12Claims
0Family size
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Key dates
| Filing date | Jan 25, 1999 |
| Grant date | May 9, 2006 |
| Priority date | — |
| Expiry date | Jan 25, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/71
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a member of a novel gene family referred to as developmentally-regulated endothelial cell locus-1 (del-1). In particularly, the invention related to del-1 nucleotide sequences, Del-1 amino acid sequences, methods of expressing a functional gene product, and methods of using the gene and gene product. Since del-1 is expressed in endothelial cells and certain cancer cells, it may be useful as an endothelial cell and tumor marker. In addition, anti-Del-1 antibodies for immunological assessment of Del-1 protein expression as well as for inhibiting or stimulating Del-1 function are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.