Patent · US Expired

Method of monitoring a biological system by labeling with an apo metal binding protein

US7045312B2 · kind B2 · utility

1Cited by

4References

1Claims

0Family size

Inventors

Inge Dierynck · Berchem, BE
Christiaan Hubert Simon Roelant · Leuven, BE
Rudi Pauwels · Champéry, CH
Koenraad Lodewijk August Van Acker · Temse, BE
Jan Octaaf De Kerpel · Lede, BE

Key dates

Filing date	Sep 8, 2004
Grant date	May 16, 2006
Priority date	—
Expiry date	Sep 11, 2024

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/583
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.