Methods for modulating expression of exogenous genes in mammalian systems
US7045315B2 · kind B2 · utility
57Cited by
25References
41Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 7, 2001 |
| Grant date | May 16, 2006 |
| Priority date | — |
| Expiry date | Apr 29, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In accordance with the present invention, there are provided various methods for modulating the expression of an exogenous gene in an isolated cell and in a mammalian subject employing modified ecdysone receptors. Also provided are modified ecdysone receptors, as well as homomeric and heterodimeric receptors containing same, nucleic acids encoding invention modified ecdysone receptors, modified hormone response elements, gene transfer vectors, recombinant cells, and transgenic animals containing nucleic acids encoding invention modified ecdysone receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.