Methods of agonizing and antagonizing FabK

US7048926B2 · kind B2 · utility

Assignee

• Affinium Pharmaceuticals, Inc. · CA

Inventors

• Martin Brandt · North Wales, US
• Walter E. DeWolf, Jr. · Glenmoore, US
• Paul M. Keller · West Chester, US
• Arunbhai H. Patel · Colonial Beach, US
• David John Payne · Collegeville, US
• Shannon Reed · Norristown, US
• Mark A. Seefeld · Collegeville, US
• David Graham Tew · Leicester, GB
• Nicola Gail Wallis · Wayne, US
• Joshua West · Spring City, US

Key dates

• Filing date: Apr 4, 2003
• Grant date: May 23, 2006
• Expiry date: Apr 11, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides methods for using agonists and antagonists of FabK polypeptides, particularly to modulate the metabolism of bacteria or to treat bacterial infection.