Epitope-tagged beta-amyloid precursor protein and DNA encoding the same
US7049138B2 · kind B2 · utility
4Cited by
5References
3Claims
0Family size
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Key dates
| Filing date | Dec 20, 2002 |
| Grant date | May 23, 2006 |
| Priority date | — |
| Expiry date | Jul 22, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed generally to methods and composition for monitoring the processing of epitope-tagged beta-APP. More specifically, the present invention relates to the use of such methods and composition for monitoring responses of cells expressing such epitope-tagged beta-APP or fragments thereof or cell free systems containing the epitope-tagged polypeptides to therapy of diseases associated with an altered metabolism of the beta amyloid precursor protein (APP), and for screening and evaluation of potential drugs for the treatment of these disorders, including Alzheimer's disease (AD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.