Compounds and use thereof to modify transport across cell membranes
US7049295B2 · kind B2 · utility
4Cited by
0References
3Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 21, 2000 |
| Grant date | May 23, 2006 |
| Priority date | — |
| Expiry date | Mar 22, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides the use of a compound capable of preferential interaction with plasma membrane lipid microdomains (PMLMs) as enhancers of transport processes across endothelial, epithelial and mesothelial membranes (ie including blood-brain-blood barrier and gastrointestinal mucosal membranes). When associated with therapeutic agents, the compounds act as transport vehicles. When the compounds interact with PMLMs in such a way as to inhibit transport across the membrane, the compounds function as anti-infective agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.