Substituted thiophenes: compositions, processes of making, and uses in disease treatment and diagnosis

US7049333B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Hans-Jochen Lang · Hofheim, DE
• Uwe Heinelt · Wiesbaden, DE
• Armin Hofmeister · Frankfurt, DE
• Klaus Wirth · Frankfurt am Main, DE
• Michael Gekle · Coburg, DE
• Markus Bleich · Brechen, DE

Key dates

• Filing date: May 30, 2003
• Grant date: May 23, 2006
• Expiry date: Jun 7, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted thiophenes, processes for their preparation, their use as medicament or diagnostic agent. The substituted thiophene derivatives have the following backbone structure: Medicaments comprising compounds of this type are of use for preventing or treating various disorders, such as, respiratory disorders and snoring, acute and chronic disorders, disorders induced by ischemic and/or reperfusion events and by proliferative or fibrotic events, disorders of the central nervous system and lipid metabolism, diabetes, blood coagulation and infection by parasites.