Stabilized radiopharmaceutical compositions
US7052672B2 · kind B2 · utility
6Cited by
8References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 11, 2001 |
| Grant date | May 30, 2006 |
| Priority date | — |
| Expiry date | Jan 13, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to stabilized 99mTc radiopharmaceutical compositions, which include both a radioprotectant and one or more antimicrobial preservative(s), and hence have an extended lifetime of use. The radioprotectant is ascorbic acid, para-aminobenzoic acid, gentisic acid or a salt thereof with a biocompatible cation, and the antimicrobial preservative is one or more compound from the paraben series of preservatives. The invention is particularly useful for cationic, lipophilic 99mTc heart imaging agents such as Myoview™.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.