CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker in alzheimer's disease
US7052852B1 · kind B1 · utility
4Cited by
1References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 30, 2003 |
| Grant date | May 30, 2006 |
| Priority date | — |
| Expiry date | May 19, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for assessing the risk of developing Alzheimer's Disease (AD), for diagnosing AD, and for measuring the progression of AD in a patient by determining CD45 isoform expression of blood cells obtained from the patient. The methods of the invention include determining CD45 isoform expression by cytometric analysis, quantitative Western immunoblotting, or quantitative RT-PCR or combinations thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.