Purified LH
US7053054B2 · kind B2 · utility
2Cited by
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10Claims
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Key dates
| Filing date | Jan 22, 2001 |
| Grant date | May 30, 2006 |
| Priority date | — |
| Expiry date | May 9, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for the purification of recombinant human Luteinizing Hormone (LH) from a sample of crude recombinant LH in the supernatant of CHO cells comprises the combined use of the ion-exchange chromatography and reverse phase HPLC. The ion-exchange chromatography and the reverse phase HPLC are performed twice and the final use of a gel permeation column allows the purification from any residual traces of contaminants. The specific bioactivity of the highly purified LH obtained from the process is particularly high, amounting to 25,000 IU/mg.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.