Compounds of unstable DP IV-inhibitors

US7053055B2 · kind B2 · utility

Assignee

• Prosidion Limited · GB

Inventors

• Hans-Ulrich Demuth · Halle (Saale), DE
• Jorn M. Schmidt · Nordborg, DK
• Torsten Hoffmann · Weil am Rhein, DE
• Konrad Glund · Halle (Saale), DE

Key dates

• Filing date: Dec 21, 2000
• Grant date: May 30, 2006
• Expiry date: Jul 26, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of unstable inhibitors of the serine peptidase dipeptidyl peptidase IV, are used in the treatment of various disorders, especially of metabolic disorders. The compounds can be used in the treatment of impaired glucose tolerance, glucosuria, hyperlipidaemia, metabolic acidoses, diabetes mellitus, diabetic neuropathy and nephropathy.