Controlled electroporation and mass transfer across cell membranes in tissue
US7053063B2 · kind B2 · utility
109Cited by
9References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 2005 |
| Grant date | May 30, 2006 |
| Priority date | — |
| Expiry date | May 26, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0476
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Electroporation is performed in a controlled manner in individual and multiple biological cells present in biological tissue by monitoring the electrical impedance, defined herein as the ratio of current to voltage in the electroporation cell. The impedance detects the onset of electroporation in the biological cell(s), and this information is used to control the intensity and duration of the voltage to assure that electroporation has occurred without destroying the cell(s). This is applicable to electroporation in general.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.