Locked nucleic acid containing heteropolymers and related methods
US7053195B1 · kind B1 · utility
115Cited by
7References
52Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 10, 2002 |
| Grant date | May 30, 2006 |
| Priority date | — |
| Expiry date | Aug 10, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to methods of replacing nucleotides in target nucleic acid sequences using DNA-LNA chimeras. The method of the present invention provides for replacing a first nucleotide in a target sequence by exposing the target sequence to a DNA-LNA heteropolymer and thereby replacing the first nucleotide with a second nucleotide. The invention also features the DNA-LNA chimeras themselves as well as methods of making them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.