Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them

US7053217B2 · kind B2 · utility

Assignee

• DR. REDDY'S LABORATORIES LIMITED · IN

Inventors

• Ranga Madhavan Gurram · Hyderabad, IN
• Venkateswarlu Akella · Darsi, IN
• Rajagopalan Ramanujam · Hyderabad, IN
• Ranjan Chakrabarti · Hyderabad, IN
• Parimal Misra · Hyderabad, IN
• Vidya Bhushan Lohray · Hyderabad, IN
• Braj Bhushan Lohray · Hyderabad, IN
• Rao Bheema Paraselli · Hyderabad, IN

Key dates

• Filing date: Jan 8, 2002
• Grant date: May 30, 2006
• Expiry date: Mar 10, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/90
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel β-aryl-α-oxysubstituted alkylcarboxylic acids of the general formula (I),their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. The present invention also relates to a process for the preparation of the above said novel compounds, their analogs, their derivatives, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to novel intermediates, processes for their preparation and their use in the preparation of compounds of formula (I).