Drug delivery platform

US7056339B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Christopher Elkins · Chapel Hill, US
• Michael D. Dake · Stanford, US
• Jacob M. Waugh · Mountain View, US

Key dates

• Filing date: Mar 11, 2002
• Grant date: Jun 6, 2006
• Expiry date: Dec 14, 2023

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B33Y80/00
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A stent based drug delivery system. A biological agent of interest is entrapped within a matrix, which is loaded into channels on the surface of a stent. The matrix allows for release, usually sustained release, of the entrapped agent. The stent and matrix is sheathed with a covalently bound gel. In one embodiment of the invention, the stent is used to deliver therapeutic agents to a patient, providing the advantage of efficient delivery and sustained release of an agent at a localized site. In another embodiment of the invention, the drug delivery system is used for testing and comparison of candidate drugs in an in vivo setting.